Upstream created six principles for prioritizing reuse and refill within EPR and Deposit Return Systems (DRS). The principles emphasize the need for flexibility to meet individual states' needs and are listed below, with more in-depth information on Upstream's website.

1. Institutionalize reuse through producer funding and financial incentives
2. Mandate and measure reuse
3. Enact DRS and EPR as complementary policies
4. Clearly define "reusable" packaging
5. Center justice and equity in process and content
6. Allow flexibility; avoid barriers to reuse